Clinical Studies

This clinical trial aims to evaluate an investigational, orally administered veterinary drug for itching associated with atopic dermatitis, or skin inflammation, in dogs.

This clinical trial will evaluate the effectiveness of a novel investigational product for the treatment of oral melanoma in dogs.

Xylitol is an artificial sweetener commonly found in sugar-free gum. Although safe for humans, xylitol is highly toxic to dogs. This study will compare the liver protective capacity of two veterinary liver protectant products in dogs suffering from xylitol toxicity.

Necrotizing Meningoencephalitis in Pugs (PDE) is a devastating disease. Clinical signs include seizures, circling, cognitive changes, and visual deficits. Our goal is to identify neurological abnormalities in Pugs with high genomic risk for PDE before the onset of the above-mentioned advanced clinical signs.

This study seeks to define the rate at which methylnaltrexone (MNTX) is metabolized in dogs following intravenous administration. Postoperative regurgitation is a common side effect of general anesthesia. The opioid-inhibiting effects of MNTX block the risk of opioid-related complications, without reducing pain control and pain management.

Current chemotherapy treatments involve a direct injection into the tumor. We would like to use surgically removed lung tissue to better understand how drugs behave when they are injected into lung tumors in dogs, as well as humans, with lung tumors.

This study will evaluate the safety and effectiveness of a newly proposed anti-inflammatory drug in dogs experiencing mild acute onset pancreatitis (AOP) symptoms.

We are studying a novel live probiotic product typically found in the gut of healthy dogs to evaluate the ability of this probiotic to resolve diarrhea in dogs.

Development of a safe and beneficial immunotherapy option for canine urothelial carcinoma patients will advance veterinarians' ability to treat this disease and will provide an important model to inform future canine and human clinical trials in this area.

A new veterinary device composed of collagen and elastin particles has been developed; it has been shown to help protect cartilage from mechanical grinding. Previous anecdotal use of this product has been beneficial in dogs with elbow dysplasia.

This study aims to determine whether or not canine patients diagnosed with canine osteosarcoma (OSA) have intestinal dysbiosis and whether treating intestinal disease improves patient outcomes.

Is your dog undergoing surgery for a ruptured splenic tumor? Ethos Discovery would love to have you and your dog participate in our clinical trial! We are evaluating drugs for the treatment of HSA with the goal of curing this aggressive cancer.