Clinical Studies
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K9 Tumor And Blood Sampling for Osteosarcoma and Oral Melanoma (KABOOM)
OpenNaturally occurring cancers in dogs have been as used as models for human cancers for many reasons; however, the genomic profiles of many of these cancers are still incompletely understood. Further definition of these genomic landscapes will allow for improved development of novel diagnostics and therapeutics to diagnose and treat these cancers. The objective of this
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Tolerability of Oral Paclitaxel in Cancer-Bearing Dogs
ClosedResearch Type Ethos Discovery De Novo Study Description Paclitaxel is a human chemotherapeutic that has demonstrated a broad spectrum of activity against several human and canine cancers. Previous formulations of paclitaxel have been poorly absorbed in dogs, limiting its therapeutic value. Oraxol is a novel oral formulation of paclitaxel that is combined with a second
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Canine Lymphoma – Alternating Doxorubicin and TANOVEA®-CA1 for Dogs with Untreated Lymphoma
ClosedThis study may provide information on a multi-drug treatment protocol that may result in improved outcomes for dogs with multicentric lymphoma.
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Canine Mast Cell Tumor Study
ClosedThis study will evaluate whether or not a small biopsy from a mast cell tumor is accurate for prognostication purposes.
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Chronic Cannabidiol Administration and its Therapeutic Effect in Canine Epilepsy
ClosedThis study is looking to evaluate the pharmacology profile of CBD in dogs (i.e. how it’s processed in the body) as well as its effectiveness in treating pain in dogs with chronic osteoarthritis. This study will hopefully result in similar studies being conducted in the fields of Neurology and Oncology.
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Collection of Biological Specimens from Dogs Scheduled for Biopsy or Surgery for Suspected or Known Cancer
ClosedThis study will compare certain markers in the blood that are specific to cancer, but not found in healthy dogs, before and after surgical biopsy or surgical removal of a mass.
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DIABETIC Dog Study
OpenWe are investigating a new diet that may potentially improve glycemic control in dogs with moderately controlled diabetes.
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DIABETIC Cat Study
ClosedWe are investigating a new diet that may potentially induce insulin remission in cats with newly diagnosed diabetes.
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SEPSIS Clinical Study
OpenThis study aims to evaluate changes in a specific blood hormone that has previously been related to sepsis diagnosis in canine patients surgically treated for sepsis in the abdomen and in healthy dogs with intestinal obstructions that are being surgically removed. We are investigating possible novel markers for sepsis with the goal of developing new diagnostic tests.
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Trial Evaluating an Investigational Agent for Management of Transitional Cell Carcinoma
ClosedThis trial is designed to evaluate the safety and preliminary pain management and anti-cancer effectiveness of a novel therapy in dogs with bladder transitional cell carcinoma (TCC).
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Validation of a Genomic Marker for Necrotizing Meningoencephalitis in Pugs
ClosedSingle Day Clinic: March 7, 2020.
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Ethos Discovery is pursuing an investigation into the use of a novel therapy for NME in pugs. This study will only consist of a one-time visit for the blood sample collection. Participating pugs will get free wellness and neurological exams, general bloodwork, and NME-risk factor screening. -
Rapamycin for the Treatment of Cancer in Dogs
OpenThis study seeks to understand the intestinal absorption potential of a novel formulation of rapamycin when administered to dogs with naturally occurring cancer. The data from this study will be used to define an ideal dose of the drug to use in future cancer clinical studies.
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