Evaluating Benefit of a Novel Intra-articular Device in Dogs With a Suspected Cruciate Ligament Tear
Currently EnrollingAnnouncing a fully funded clinical trial for dogs with suspected cranial cruciate ligament injuries who will not be pursuing surgery
Cranial cruciate ligament disease is a complex, multifactorial disease characterized by disruption of the ligament leading to stifle instability. Surgical procedures to alter joint mechanics are often costly, which can preclude some owners from pursuing this as a treatment option. A novel veterinary device has been developed that is composed of collagen and elastin particles and is delivered via intra-articular injection to help protect cartilage from mechanical grinding. Previous anecdotal use with this product has suggested a possible benefit when used in dogs with cruciate injuries.
This pilot study seeks to determine whether this benefit is seen in a larger cohort of dogs with suspected cranial cruciate ligament rupture through the intra-articular injection of this product in the affected stifle joint. If a benefit is demonstrated, this data would support the launch of larger and more focused clinical trials to validate the use of this product in dogs for the pre-surgical management of cruciate disease.
Pet owners and veterinarians with eligible patients are invited to schedule a consultation with one of the surgeons listed below.
Eligibility Criteria:
- Dogs that are 6 months of age or older
- Limping on hindlimb that is suspected to be due to a partially or fully torn cranial cruciate ligament
- No previous surgical procedures on the affected joint within 180 days of entering the study
- No -intra-articular injections within 90 days prior to the study
- No treatments with topical or systemic drugs that have analgesic or anti-inflammatory properties within 3 days prior to the study (study allows for rescue analgesics to be used per protocol if needed)
- No injectable corticosteroids or administration of polysulfated glycosaminoglycans, glucosamine, or chondroitin sulfate nutritional supplements within 30 days prior to enrollment
- No pregnant or lactating dogs
Study period:
- 84 days with 8 study visits
Incentive:
- Fully funded (no costs to owner)
Participating Hospitals:
If you have any clients with eligible patients who would be interested to learn more about the study, please have them schedule a consultation appointment with the surgeon and hospital of their choice below.
- Bulger Veterinary Hospital, Lawrence, MA
- Massachusetts Veterinary Referral Hospital, Woburn, MA
- VSH-Sorrento Valley, San Diego, CA
- WVRC – Racine/Kenosha, Somers, WI
- WVRC – Waukesha, Waukesha, WI
Interested?
Enroll or request more information below